SKU DS4004 · Fasting Mimicking Diet
L-Biome (Intestinal Health)
L-Biome was developed by scientists at the Longevity Institute at the University of Southern California in collaboration with doctors at L-Nutra.
It is designed for the post 5-day ProLon fasting microbiome, from a combination of prebiotics, probiotics and DHA, all in a single daily capsule, thanks to advanced technology.
L-Biome is a supplement of Bifidobacterium Breve B3, Lactobacillus Rhamnosus HN001, Inulin and DHA.
- Rich in live friendly bacteria
- Supports healthy fasting microbiome programme
- Functional prebiotics
- Supports short-chain fatty acid production
- Promotes healthy gut barrier integrity
- +Supports digestive health
Nutritional Fact Information
Ships from Lonso Milan facility · 72h after order confirmation · free cold-chain shipping on orders over €1,500.
Post-fast microbiome
Mirrors the beneficial strains that flourish after a 5-day Prolon FMD.
Gut barrier integrity
Lactobacillus rhamnosus HN001 supports a healthy intestinal barrier and gut-immune axis.
Daily routine
Two capsules with a meal. Resume after each refeed day to extend FMD benefits.
How it fits the protocol
Best after a fast. Every day, between cycles.
01
Before the cycle
Optional priming phase — patients can start L-Biome 1 week before their first Prolon FMD to baseline gut microbiota.
02
Day 6 — refeed
Start L-Biome on the morning after the 5-day FMD. This is the moment the post-fasting microbiome is most receptive to new colonisation.
03
Daily, ongoing
Two capsules with a meal. Patients aged 18–80, daily, between FMD cycles or as a long-term gut- health routine.
What's in the capsule
Two probiotics, one prebiotic, plus DHA —the post-FMD microbiome
The quality and rate of our biological aging are the main determinants of a long and healthy life. L-Biome's strength lies in its unique combination of probiotics, prebiotic fibre and DHA that help re-establish a healthy gut microbiome after fasting.
PER 2 CAPS
Per 2 caps
Morinaga B-3®
Bifidobacterium breve B-3
Clinical tests have shown that B-3 reduced fat mass in adults with a tendency to obesity. Supports body weight, blood glucose, insulin and cholesterol levels within a normal range — one of the essential microbiota that develops after the 5-day FMD.
PER 2 CAPS
16 bnCFU
LactoB HN001™
Lactobacillus rhamnosus HN001
Particularly resistant to bile, allowing it to colonise the upper small intestine and colon. Supports healthy digestive function, intestinal barrier integrity, the gut-immune axis, and healthy nutrient absorption — flourishes after Prolon's fasting nutrition.
PER 2 CAPS
1,200 mg
Inulin
Plant-derived prebiotic fibre
Insoluble fibre that nourishes the probiotic flora and promotes its growth. The same prebiotic used inside the 5-day Prolon FMD — addresses the fibre deficit common in modern processed-food diets.
PER 2 CAPS
300 mg
DHA · Algal Oil
Schizochytrium sp.
An essential omega-3 polyunsaturated fatty acid. Structural component of the brain and retina, with positive influence on the gut-brain axis, intestinal wall integrity and immune health. 100% plant-based — sourced from algae, not fish.
DUAL-CAP TECHNOLOGY
Two compartments.
Two release profiles.
One capsule.
L-Biome is equipped with dual-cap technology to ensure that patients get the optimum dosage of each ingredient in a safe and effective way.
Outer shell
DHA, housed for immediate absorption on contact with the digestive tract.
Inner capsule
Probiotic strains and inulin prebiotic fibre — encased and released gradually.
Net result
Patients absorb DHA quickly, then receive steady probiotic and prebiotic support across hours.
Biological Age Score · Nature Aging, 2024
Three cycles. 2.5 years younger, on the data.
In the Mishra et al. 2024 trial (n=144, RCT), patients completing three consecutive Prolon FMD cycles reduced their Levine PhenoAge by an average of 2.5 years versus controls.
3 yrs
Biological Age Δ
−1.30 pp
HBA1C (12 wk)
−7.4%
Trunk Fat
96%
1st-Cycle Completion
- Morinaga B-3® (Bifidobacterium breve B-3): Probiotic strain that supports body weight, blood glucose, insulin and cholesterol within a normal range.
- LactoB HN001™ (Lactobacillus rhamnosus HN001): Bile-resistant probiotic that supports digestive function, gut barrier integrity and the gut-immune axis.
- Inulin: Plant-derived prebiotic fibre that nourishes the probiotic flora and promotes its growth.
- DHA · Algal Oil: Plant-based omega-3 supporting the gut-brain axis, intestinal wall integrity and immune health.
Complete the Protocol