The Science

The science behind ProLon.

Our 5-day nutrition program is the only patented program clinically shown to promote rejuvenation from within for healthy aging.

Eat, while your cells fast.

ProLon is a plant-based nutrition program developed at the Longevity Institute at the University of Southern California (USC). It allows the body to enter a fasting state without triggering the cells' nutrient sensors — so you keep eating real food while your cells stay in fasting mode.

The 5-Day Program

Five days of food. A measurable cellular reset.

1100 kcal

D1

Transition

The body enters a fasting state and begins switching to fat-burning mode.

770 kcal

D2

Fat-burning & ketogenesis

Fat burning increases; ketosis may begin around 48 hours.

770 kcal

D3

Autophagy / cleanup

Cellular cleanup begins; fat burning and ketone production increase.

770 kcal

D4

Cellular rejuvenation

Cellular renewal continues; cells begin to resemble younger versions.

770 kcal

D5

Renewal & remodeling

Cellular renewal continues beyond day 5; ketosis can be sustained.

Precision Nutrition

Macro- and micro-precision nutrition keeps you in a fasting state.

The Fasting Mimicking Diet uses specific ratios of plant proteins, healthy fats, and complex carbohydrates. Because the ingredients don't activate the cell's nutrient-sensing pathways, you can keep eating while your cells remain in a fasting state.

Every ingredient is tested and carefully selected.

Autophagy

Activate autophagy — the magic of cellular rejuvenation.

Fasting triggers autophagy — the body's process of clearing out old cellular components to make room for new, healthy ones. ProLon supports this natural cellular cleanup and renewal.

Autophagy is so important for health and longevity that research on the subject was awarded the 2016 Nobel Prize in Medicine.

Clinically validated

Clinically tested and proven to promote healthy aging.

20+ years

Research & development

Two decades of research at USC's Longevity Institute.

Peer-reviewed

Published science

Findings published in leading scientific journals.

Patented

The original FMD

The only patented Fasting Mimicking Diet.

Trusted by clinicians

What the experts say.

ProLon offers so many benefits for weight, metabolism, and cellular health that I not only recommend it — I decided to join the company's mission full-time as Chief Medical Officer.
Dr. William Hsu, M.D.

Dr. William Hsu, M.D.

Chief Medical Officer

I love the science behind ProLon, and I love that it has been published in several peer-reviewed scientific journals. ProLon takes this and brings it to a higher level.
Dr. Amy Savagian, M.D.

Dr. Amy Savagian, M.D.

Physician

I not only recommend ProLon as a frequent nutritional intervention — I've tried it myself many times. I love this product so much that I invested in the company.
Dr. Maria Tulpan, M.D.

Dr. Maria Tulpan, M.D.

Physician