The Science
The science behind ProLon.
Our 5-day nutrition program is the only patented program clinically shown to promote rejuvenation from within for healthy aging.
Eat, while your cells fast.
ProLon is a plant-based nutrition program developed at the Longevity Institute at the University of Southern California (USC). It allows the body to enter a fasting state without triggering the cells' nutrient sensors — so you keep eating real food while your cells stay in fasting mode.
The 5-Day Program
Five days of food. A measurable cellular reset.
1100 kcal
D1
Transition
The body enters a fasting state and begins switching to fat-burning mode.
770 kcal
D2
Fat-burning & ketogenesis
Fat burning increases; ketosis may begin around 48 hours.
770 kcal
D3
Autophagy / cleanup
Cellular cleanup begins; fat burning and ketone production increase.
770 kcal
D4
Cellular rejuvenation
Cellular renewal continues; cells begin to resemble younger versions.
770 kcal
D5
Renewal & remodeling
Cellular renewal continues beyond day 5; ketosis can be sustained.
Precision Nutrition
Macro- and micro-precision nutrition keeps you in a fasting state.
The Fasting Mimicking Diet uses specific ratios of plant proteins, healthy fats, and complex carbohydrates. Because the ingredients don't activate the cell's nutrient-sensing pathways, you can keep eating while your cells remain in a fasting state.
Every ingredient is tested and carefully selected.
Autophagy
Activate autophagy — the magic of cellular rejuvenation.
Fasting triggers autophagy — the body's process of clearing out old cellular components to make room for new, healthy ones. ProLon supports this natural cellular cleanup and renewal.
Clinically validated
Clinically tested and proven to promote healthy aging.
20+ years
Research & development
Two decades of research at USC's Longevity Institute.
Peer-reviewed
Published science
Findings published in leading scientific journals.
Patented
The original FMD
The only patented Fasting Mimicking Diet.
Trusted by clinicians
What the experts say.
ProLon offers so many benefits for weight, metabolism, and cellular health that I not only recommend it — I decided to join the company's mission full-time as Chief Medical Officer.

Dr. William Hsu, M.D.
Chief Medical Officer
I love the science behind ProLon, and I love that it has been published in several peer-reviewed scientific journals. ProLon takes this and brings it to a higher level.

Dr. Amy Savagian, M.D.
Physician
I not only recommend ProLon as a frequent nutritional intervention — I've tried it myself many times. I love this product so much that I invested in the company.

Dr. Maria Tulpan, M.D.
Physician







